This scientific discipline focuses on identifying and manipulating the fundamental biochemical and cellular processes responsible for biological aging and senescence. It is a research area dedicated to understanding how molecular damage accumulates and how these processes can be therapeutically modulated. The goal is to develop interventions that slow the rate of biological decline, promoting a longer healthspan.
Origin
The field emerged from breakthroughs in genetics, biochemistry, and cell biology, particularly the identification of conserved aging pathways like mTOR, sirtuins, and AMPK across various organisms. Its roots are firmly planted in basic research, which seeks to translate molecular findings into clinical strategies for human longevity.
Mechanism
Core mechanisms involve the study of epigenetic alterations, mitochondrial dysfunction, and proteostasis imbalance. Molecular scientists investigate small molecules, peptides, and gene therapies designed to restore youthful cellular function, enhance DNA repair, and improve mitochondrial efficiency, directly targeting the molecular drivers of age-related pathology.
Standardized wellness goals are biologically inequitable because individual pharmacogenomics dictate a unique metabolic response to any fixed protocol.
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