Anti-Aging Medicine Science is a clinical and translational discipline focused on the early detection, prevention, and treatment of age-related dysfunction, disease, and infirmity. This science applies advanced biomedical technologies and evidence-based interventions to optimize human physiological function and slow the biological aging process. The goal is to extend the healthspan, the period of life spent in good health, high function, and vitality, rather than simply extending lifespan.
Origin
This field originated from the confluence of traditional gerontology, endocrinology, and preventative medicine, gaining significant momentum in the late 20th century with the recognition of hormones and cellular senescence as modifiable factors. The term “Anti-Aging” was popularized to distinguish this proactive, interventional approach from the passive management of age-related diseases. It is rooted in the scientific understanding of the molecular and cellular hallmarks of aging.
Mechanism
The core mechanisms addressed include mitigating telomere shortening, improving mitochondrial efficiency, reducing chronic systemic inflammation, and restoring youthful hormonal profiles. Clinical interventions often involve bio-identical hormone replacement therapy, targeted nutritional supplementation, and lifestyle modifications designed to modulate epigenetic expression. The science operates by influencing fundamental biological pathways that govern cellular repair and regeneration.
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