The scientific discipline focused on developing and studying methods—pharmacological, lifestyle, and genetic—to slow, halt, or reverse the biological processes of aging. This field seeks to extend the period of healthy life, known as healthspan, by targeting the molecular and cellular hallmarks of senescence. Clinical applications often involve hormonal modulation and metabolic optimization to restore youthful physiological function. Understanding the complex interplay of the endocrine system is central to effective anti-aging strategies.
Origin
The concept evolves from gerontology, the study of aging, and has been amplified by advancements in molecular biology and endocrinology in the late 20th and early 21st centuries. The term specifically highlights the shift from merely studying aging to actively intervening in its underlying biological mechanisms. It represents an interdisciplinary convergence of longevity research, regenerative medicine, and clinical endocrinology.
Mechanism
Interventions operate by targeting fundamental aging pathways, such as telomere attrition, mitochondrial dysfunction, cellular senescence, and altered intercellular communication. Strategies often involve modulating key endocrine axes, including the Growth Hormone/IGF-1 axis or sex steroid hormones, to promote tissue repair and cellular vitality. The goal is to enhance the body’s intrinsic repair mechanisms and maintain systemic hormonal balance, thereby improving overall physiological resilience.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.