The precise tailoring of a longevity protocol to target a patient’s unique, measurable biological aging mechanisms, rather than applying a general, broad-spectrum treatment. This approach mandates diagnostic clarity to identify the specific cellular or hormonal deficit driving an individual’s aging phenotype. Specificity ensures that interventions are maximally effective and metabolically efficient.
Origin
Emerges from the paradigm shift in gerontology and precision medicine, moving beyond generalized supplementation toward personalized molecular and endocrine modulation. The core principle acknowledges that aging is a heterogenous process, necessitating specific, mechanism-based therapeutic actions for maximal efficacy. This concept drives the development of highly individualized treatment plans.
Mechanism
Requires comprehensive biomarker analysis, including telomere length, epigenetic clocks, and detailed hormonal panels, to pinpoint the most compromised biological pathway, such as mitochondrial dysfunction or senescent cell burden. The intervention is then specifically directed to modulate that precise pathway, thereby optimizing the therapeutic index and minimizing off-target effects. This focused approach yields superior and more predictable clinical outcomes.
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