What is the Origin of Anti-Aging Compounds?

The term originates from the burgeoning field of gerontology and biogerontology, which applies molecular biology and physiology to the study of aging. The pursuit of such compounds accelerated with the identification of conserved aging pathways in various organisms. This research area integrates traditional pharmacology with nutritional science, seeking agents that mimic the protective effects of caloric restriction.

What is the Mechanism of Anti-Aging Compounds?

These compounds function by targeting key molecular pathways implicated in senescence and age-related pathology. Common mechanisms include enhancing cellular stress resistance, promoting DNA repair fidelity, modulating nutrient sensing pathways like mTOR and AMPK, and boosting mitochondrial function. Specific compounds may act as NAD+ precursors, activate sirtuins, or directly scavenge reactive oxygen species, thereby preserving cellular function and delaying the onset of age-related disease.

Anti-Aging Compounds

Meaning

Anti-Aging Compounds are a class of bioactive molecules, including natural and synthetic substances, investigated for their potential to counteract the physiological hallmarks of cellular and systemic aging. These compounds are studied in the context of longevity science and aim to modulate biological pathways associated with age-related decline. The focus is on improving healthspan, which is the period of life spent in good health, rather than merely extending lifespan. Clinical interest centers on their capacity to enhance cellular function and maintain tissue integrity over time.