Anti-Aging Chemical Ecology is a conceptual framework that examines the dynamic interplay of endogenous and exogenous chemical signals that influence the rate of biological aging and overall longevity. This perspective integrates the study of hormones, neurotransmitters, metabolites, and environmental xenobiotics as a cohesive system governing cellular senescence and healthspan. Clinical translation involves optimizing this internal chemical environment for maximal physiological resilience.
Origin
The term synthesizes principles from endocrinology, toxicology, and the broader field of gerontology, applying an ecological lens to the body’s internal chemical landscape. It moves beyond single-target interventions to consider the synergistic and antagonistic effects of a vast network of chemical messengers. This holistic view acknowledges the profound impact of the exposome on the human endocrine system and cellular health.
Mechanism
This ecology is fundamentally regulated by the balance between pro-inflammatory and anti-inflammatory signaling pathways, often mediated by hormonal status. Key regulatory nodes include the hypothalamic-pituitary-adrenal (HPA) axis and the insulin/IGF-1 signaling cascade, which are highly sensitive to both internal and external chemical stressors. Optimizing this chemical ecology involves targeted interventions to restore homeostatic balance, dampen chronic low-grade inflammation, and enhance cellular repair processes.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.