The systematic laboratory assessment of specific molecular, cellular, or physiological indicators that correlate with an individual’s biological age and rate of senescence. This analysis moves beyond chronological age to provide a precise, quantitative measure of healthspan and physiological reserve. The findings inform personalized strategies aimed at decelerating the aging process.
Origin
The practice originates from advances in molecular biology and clinical chemistry, enabling the precise measurement of aging-related cellular damage and systemic dysfunction. It is a core component of precision medicine and proactive longevity protocols.
Mechanism
The process involves evaluating biomarkers such as telomere length, DNA methylation patterns (epigenetic clocks), circulating inflammatory cytokines, and critical hormonal concentrations. By comparing an individual’s biomarker profile to established age-specific norms, clinicians can identify areas of accelerated aging. These objective metrics guide targeted interventions to restore optimal biological function.
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