What is the Origin of Anorexigenic Effects?

The term is derived from the Greek words "an-," meaning "without," and "orexis," meaning "appetite," combined with the suffix "-genic," meaning "producing." It is a concept central to neuroendocrinology, a field that studies the complex interplay between the nervous system and the endocrine system in regulating energy homeostasis. Key anorexigenic signals include hormones like Leptin, Peptide YY (PYY), and Cholecystokinin (CCK).

What is the Mechanism of Anorexigenic Effects?

The mechanism involves the release of anorexigenic hormones, typically post-prandially, from the gastrointestinal tract or adipose tissue, which then travel through the bloodstream to the brain. These messengers primarily target the arcuate nucleus of the hypothalamus, where they stimulate the production and release of anorexigenic neuropeptides, such as pro-opiomelanocortin (POMC). This central signaling pathway acts to suppress the activity of hunger-promoting neurons, effectively signaling to the body that energy stores are sufficient and food consumption should cease.

Anorexigenic Effects ∞ Area

Anorexigenic Effects

Meaning

Anorexigenic Effects are the physiological outcomes that lead to a reduction in appetite and subsequent decrease in food intake. These effects are mediated by specific neuroendocrine signals, often peptides and hormones, that act on the central nervous system to promote a feeling of satiety or fullness. Hormonal health and wellness strategies often leverage these effects to support weight management and improve metabolic parameters in individuals. The clinical relevance lies in understanding and utilizing these natural biological mechanisms to regulate energy balance effectively.