What is the Origin of Angiogenesis Stimulation Therapy?

The term is derived from the Greek words angeion (vessel) and genesis (creation), describing the physiological process of blood vessel formation. When combined with "Stimulation Therapy," it refers to the clinical practice of intentionally leveraging this natural biological process for therapeutic benefit. This concept has deep roots in cardiovascular research, wound care, and regenerative medicine.

What is the Mechanism of Angiogenesis Stimulation Therapy?

The therapy typically involves the targeted delivery of pro-angiogenic growth factors, such as Vascular Endothelial Growth Factor (VEGF) or Fibroblast Growth Factor (FGF), to the affected site. These factors bind to their respective endothelial cell receptors, triggering a complex signaling cascade that includes endothelial cell migration, proliferation, and the subsequent formation of a new capillary network. Effective stimulation relies on precise dosing and localized delivery to ensure functional, stable vessel growth.

Angiogenesis Stimulation Therapy ∞ Area

Angiogenesis Stimulation Therapy

Meaning

A specialized therapeutic approach designed to promote the formation of new blood vessels from pre-existing vasculature within ischemic or damaged tissues. This process is a fundamental biological response to inadequate blood supply, crucial for tissue repair, wound healing, and regeneration. Clinical application aims to restore proper perfusion and oxygenation to areas compromised by aging or disease, thereby improving tissue function and viability.