Skip to main content

Andropause Pathophysiology

Meaning

Andropause pathophysiology describes the biological mechanisms and functional changes underlying the age-related decline in male reproductive and hormonal function, often termed late-onset hypogonadism. This process is characterized primarily by a gradual reduction in circulating testosterone levels, a phenomenon distinct from the rapid hormonal shift of menopause. The complex interplay of primary, secondary, and tertiary factors contributes to the diverse clinical symptoms observed in aging men. Understanding the pathophysiology is essential for accurate diagnosis and targeted endocrine intervention.