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Andropause Metabolic Shift

Meaning

The Andropause Metabolic Shift denotes the cluster of adverse physiological and biochemical changes that frequently accompany the age-related decline in androgen levels in men, often referred to as andropause. This complex shift is characterized by a tendency toward increased visceral adiposity, decreased insulin sensitivity, and an unfavorable lipid profile. The resulting metabolic dysregulation significantly elevates the risk for cardiovascular disease, type 2 diabetes, and sarcopenia. Understanding this shift is critical for developing preventative and therapeutic strategies in men’s hormonal health. It represents a fundamental alteration in energy partitioning and utilization.