Clinical strategies designed to mitigate or prevent cognitive decline associated with the age-related decline in androgen production, commonly termed andropause. This support focuses on maintaining neuroplasticity, synaptic function, and cerebral blood flow, all potentially influenced by declining testosterone levels. We address deficits in executive function, memory consolidation, and mental processing speed. Successful support ensures the central nervous system benefits from adequate hormonal support during this physiological transition.
Origin
The term merges “Andropause,” referencing the gradual decrease in male gonadal function with age, with “Cognitive Support,” indicating targeted neurobiological assistance. Its origin lies in recognizing the established link between sex steroids, particularly testosterone, and central nervous system integrity. The concept acknowledges that cognitive changes are a potential systemic consequence of endocrine aging in men.
Mechanism
Testosterone acts as a neurosteroid, influencing neurotransmitter systems and promoting neuronal survival through mechanisms involving neurotrophic factors. Support mechanisms often involve optimizing testosterone levels within the physiological range to enhance hippocampal function and modulate inflammatory cytokines in the brain. Furthermore, adequate androgen status supports healthy cerebral vascular tone, ensuring optimal oxygen and nutrient delivery to neural tissues. This multifaceted action preserves neuronal membrane integrity and synaptic efficacy.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.