What is the Origin of Androgens?

The term Androgen is rooted in the Greek words 'andro,' meaning man, and 'gennan,' meaning to produce or generate. This nomenclature reflects their primary role in promoting virilization, although they are biologically vital in female physiology as well. Androgens are synthesized predominantly in the testes and adrenal cortex in males, and in the ovaries and adrenal cortex in females.

What is the Mechanism of Androgens?

Androgens exert their biological effects by diffusing into target cells and binding to specific intracellular Androgen Receptors (AR), which then translocate to the nucleus to modulate gene transcription. Furthermore, testosterone can be converted into the more potent Dihydrotestosterone (DHT) by the 5-alpha reductase enzyme in certain tissues, or aromatized into Estradiol (E2). This dual-pathway mechanism allows androgens to regulate a vast array of physiological functions across multiple organ systems.

Androgens

Meaning

Androgens represent a class of steroid hormones, synthesized primarily from cholesterol, that are essential for the development and maintenance of male secondary sexual characteristics. Testosterone is the most well-known and potent androgen, but the group also includes dehydroepiandrosterone (DHEA) and androstenedione. These hormones are critical not only for male reproductive function but also for maintaining muscle mass, bone density, libido, and energy levels in both men and women.

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Can Advanced Biomarker Analysis Predict Individual Responses to Specific Wellness Interventions?

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∞ Gonadorelin Administration
∞ Healthy
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