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Androgenic Bone Remodeling

Meaning

This term describes the process of bone tissue turnover and structural change that is directly influenced by the presence and activity of androgen hormones, primarily testosterone and its derivatives. Androgens exert a crucial regulatory role in maintaining skeletal integrity, affecting both bone formation by osteoblasts and bone resorption by osteoclasts. Clinical relevance involves understanding how these hormones contribute to peak bone mass attainment during adolescence and prevent bone density loss in adulthood. Adequate androgen levels are essential for a robust and resilient skeletal architecture throughout the lifespan.