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Androgen Signaling Competence

Meaning

Androgen Signaling Competence describes the functional capacity of target cells and tissues to effectively receive, process, and respond to androgen hormones, such as testosterone and dihydrotestosterone (DHT). This critical biological state is determined not only by circulating hormone concentrations but also by the density, affinity, and proper function of the intracellular androgen receptors (AR). A high competence level ensures robust cellular response, supporting tissue maintenance and anabolic processes throughout the body.