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Androgen Replacement Kinetics

Meaning

Androgen Replacement Kinetics refers to the study of how exogenous androgen compounds, primarily testosterone, are absorbed, distributed, metabolized, and eliminated within the body during therapeutic replacement. This pharmacological discipline is crucial for determining optimal dosing regimens and administration routes to achieve stable, physiological hormone concentrations. Understanding these kinetics allows clinicians to predict steady-state levels and minimize supraphysiological peaks or sub-therapeutic troughs, ensuring patient safety and efficacy.