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Androgen Replacement Dosing

Meaning

Androgen replacement dosing is the precise, individualized clinical practice of determining and administering the appropriate amount and frequency of exogenous androgen, typically testosterone, to restore physiological circulating concentrations. This process is complex, requiring consideration of the patient’s unique pharmacokinetic profile, route of administration, and therapeutic objectives. The clinical aim is to normalize free and total testosterone levels, thereby alleviating deficiency symptoms while rigorously avoiding supraphysiological peaks and troughs.