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Androgen Receptor Specificity

Meaning

Androgen Receptor Specificity refers to the precise molecular fit between various androgenic hormones and the androgen receptor protein within target cells. This specific binding dictates the potency and the subsequent biological response, such as gene transcription, in tissues like muscle, bone, and prostate. Understanding this selectivity is crucial in endocrinology for predicting the physiological effects of endogenous and exogenous androgens.