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Androgen Receptor Gene Expression

Meaning

Androgen Receptor Gene Expression refers to the precise molecular process by which the genetic information encoded in the androgen receptor (AR) gene is transcribed into messenger RNA (mRNA) and subsequently translated into the functional AR protein. This protein is a nuclear receptor that mediates the biological effects of androgens, such as testosterone and dihydrotestosterone, across various tissues. The level of AR expression dictates the cellular sensitivity and response magnitude to circulating androgenic hormones. Clinically, variations in this expression level are implicated in conditions ranging from muscle development to prostate health and female endocrine balance.