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Androgen Receptor Function

Meaning

Androgen Receptor Function describes the intricate biological process where the intracellular androgen receptor protein binds to its cognate steroid hormones, primarily testosterone and dihydrotestosterone (DHT). This binding event triggers a signal transduction cascade that ultimately regulates the transcription of specific target genes. The proper function of this receptor is fundamental to male sexual development, the maintenance of lean muscle mass, and the regulation of bone density in both biological sexes. Optimal receptor activity is essential for systemic hormonal equilibrium.