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Androgen Receptor Efficiency

Meaning

Androgen Receptor Efficiency quantifies the cellular responsiveness to androgen hormones, such as testosterone and dihydrotestosterone (DHT), focusing on the functional effectiveness of the signal transduction pathway within the target cell. It is a critical measure of how well the androgen receptor (AR) binds to the hormone and subsequently initiates the appropriate gene transcription within the cell nucleus. High efficiency is paramount for maintaining robust androgen-dependent physiological functions, including the preservation of muscle mass, bone density, and sexual vitality across the lifespan.