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Androgen Receptor Brain Health

Meaning

Androgen Receptor Brain Health describes the critical functional state of androgen receptors (AR) within various brain regions, particularly as it relates to cognitive, mood, and neuroendocrine regulation. These receptors mediate the actions of androgens like testosterone and dihydrotestosterone, which are vital for neuronal survival, synaptic plasticity, and myelin maintenance in both males and females. Optimal AR signaling is fundamental for maintaining structural integrity and high-level performance of the central nervous system throughout the aging process. A decline in this signaling is clinically correlated with adverse neurological changes.