Question 1

What is the Meaning of AndroFeme?

Accepted Answer

AndroFeme is a commercially available transdermal cream formulation of bio-identical testosterone, specifically indicated for the therapeutic management of women. This prescription treatment is primarily used in postmenopausal women diagnosed with Hypoactive Sexual Desire Dysfunction, a condition characterized by a distressing lack of sexual desire. The product delivers a standardized dose of testosterone directly through the skin, which is a method that bypasses first-pass hepatic metabolism.

Question 2

What is the Origin of AndroFeme?

Accepted Answer

The term itself is a proprietary name for a pharmaceutical product, combining the concept of "Andro," referencing androgens like testosterone, with "Feme," referencing the female gender for whom the medication is formulated. Its clinical application arose from the recognition that endogenous testosterone levels decline significantly in women following menopause, contributing to symptoms beyond just reproductive function. The development focused on creating a physiological, low-dose replacement that avoids the supraphysiological levels often seen with formulations designed for men.

Question 3

What is the Mechanism of AndroFeme?

Accepted Answer

The mechanism involves the exogenous delivery of testosterone, which subsequently binds to androgen receptors within target tissues, including the brain and muscle, to exert its biological effects. Testosterone acts as a prohormone, and its metabolites, such as dihydrotestosterone and estradiol, also contribute to the overall pharmacological effect on energy, mood, and libido. This transdermal route ensures a steady, sustained release of the hormone into the systemic circulation, aiming to maintain serum concentrations within the premenopausal reference range.

AndroFeme

Meaning

Origin

Mechanism

How Do Testosterone Optimization Protocols Differ for Peri-Menopausal versus Post-Menopausal Women?

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