Skip to main content

Androbactome

Meaning

The Androbactome refers to the specific functional subset of the human gut microbiome that exerts a direct or indirect regulatory influence on the metabolism, bioavailability, and overall activity of androgens, such as testosterone and its derivatives. This distinct collection of microorganisms and their collective genetic capacity forms a crucial nexus between the gastrointestinal ecosystem and male hormonal health. It is an emerging concept in endocrinology, recognizing the gut-hormone axis as a significant, modifiable determinant of systemic androgen status and associated physiological outcomes. The integrity of this microbial community impacts steroid hormone recycling and excretion.