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Anastrozole Management in HRT

Meaning

The clinical strategy involving the controlled application of the aromatase inhibitor Anastrozole within Hormone Replacement Therapy protocols. This pharmacological intervention is primarily utilized to modulate supraphysiological estrogen levels that can arise from exogenous testosterone administration, particularly in men. Careful monitoring of estradiol concentrations is paramount to prevent estrogen deficiency symptoms or adverse cardiovascular and bone health outcomes. It represents a precise pharmacological intervention aimed at optimizing the testosterone-to-estrogen ratio for therapeutic efficacy and safety.