Question 1

What is the Meaning of Anabolic Steroid?

Accepted Answer

Anabolic steroids are synthetic testosterone derivatives, promoting tissue growth, primarily muscle mass, and influencing male secondary sexual characteristics. Structurally modified, they enhance anabolic effects while ideally minimizing androgenic properties. Complete separation of these actions is physiologically unattainable. They mimic natural steroid hormones, interacting with the endocrine system.

Question 2

What is the Context of Anabolic Steroid?

Accepted Answer

Within human physiology, anabolic steroids function as exogenous ligands for androgen receptors, found in skeletal muscle, bone, and reproductive tissues. Their presence influences metabolic pathways in protein synthesis and degradation, affecting nitrogen balance and cellular anabolism. They operate by modulating gene expression, a fundamental process in cellular growth.

Question 3

What is the Significance of Anabolic Steroid?

Accepted Answer

Anabolic steroids hold therapeutic significance in managing conditions like muscle wasting or androgen deficiency. Judicious medical application can improve patient quality of life by restoring muscle mass and strength. However, widespread non-medical use for performance enhancement presents substantial public health challenges due to significant health risks and dependence potential.

Question 4

What is the Mechanism of Anabolic Steroid?

Accepted Answer

Anabolic steroids primarily bind to intracellular androgen receptors in target cells. The steroid-receptor complex translocates to the nucleus, interacting with specific DNA sequences, hormone response elements. This modulates gene transcription for protein synthesis, increasing muscle protein accretion and reducing breakdown. They also stimulate erythropoiesis.

Question 5

What is the Application of Anabolic Steroid?

Accepted Answer

Therapeutically, anabolic steroids are prescribed for hypogonadism, certain anemias, and to mitigate muscle loss in chronic debilitating illnesses, under strict medical supervision. Misuse by individuals seeking to augment athletic performance or enhance body composition is common. Administration routes vary: oral, intramuscular, and transdermal.

Question 6

What is the Metric of Anabolic Steroid?

Accepted Answer

Monitoring anabolic steroid effects and levels in clinical settings involves key metrics. For therapeutic use, clinicians assess serum testosterone, lipid profiles, liver function tests (LFTs), and hematocrit for systemic impact. In suspected misuse, drug testing via urine or blood analysis detects compounds. Clinical evaluation also observes changes in body composition and screens for specific side effects.

Question 7

What is the Risk of Anabolic Steroid?

Accepted Answer

Unsupervised or improper anabolic steroid use carries considerable health risks. Adverse effects include severe cardiovascular complications (dyslipidemia, hypertension, cardiomyopathy) and hepatotoxicity, especially with oral forms. Reproductive dysfunction (testicular atrophy in males, virilization in females) is common. Psychological effects manifest as mood disturbances, aggression, and potential for dependence.

Anabolic Steroid

Meaning

Context

Significance

Mechanism

Application

Metric

Risk

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