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Anabolic Signaling Fidelity

Meaning

Anabolic Signaling Fidelity describes the precise and undistorted transmission of signals initiated by anabolic stimuli, such as testosterone or insulin, to the downstream cellular machinery responsible for growth and synthesis. High fidelity ensures that the cellular response, like protein accretion or hypertrophy, accurately reflects the intensity and duration of the initial hormonal signal received. Disturbances in this fidelity are clinically significant as they often manifest as anabolic resistance in aging or chronic disease states.