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Anabolic Resistance Syndrome

Meaning

Anabolic Resistance Syndrome describes a physiological state where the body’s tissues, especially skeletal muscle, exhibit a reduced responsiveness to growth-promoting stimuli like resistance exercise and amino acid intake. This condition fundamentally impairs the homeostatic balance necessary for efficient protein synthesis, leading to a diminished capacity for tissue repair and maintenance of lean body mass. It is a critical factor underlying age-related muscle loss and functional decline, signaling a profound cellular signaling dysfunction. The syndrome signifies a failure to fully utilize available anabolic resources, which accelerates the loss of muscle quality and strength.