This term refers to the quantifiable level of hormones within the circulatory system that promote anabolism, the metabolic process responsible for synthesizing complex molecules from simpler ones. Key anabolic hormones include testosterone, growth hormone, and insulin-like growth factor 1 (IGF-1). Maintaining optimal concentrations is crucial for tissue repair, muscle protein synthesis, and bone density maintenance, directly supporting physiological vitality.
Origin
The term combines “anabolic,” derived from the Greek anabole meaning “a building up,” with “hormone,” from the Greek hormao meaning “I excite” or “I set in motion.” “Concentration” is a clinical measure from chemistry, defining the amount of substance per unit volume. The concept is fundamental to endocrinology and clinical assessment of metabolic status.
Mechanism
Anabolic hormones exert their effects by binding to specific intracellular or membrane receptors on target cells, triggering signal transduction pathways that ultimately increase gene expression for protein synthesis. This action promotes nitrogen retention and positive energy balance, which are essential for tissue accretion and the maintenance of lean body mass. The concentration directly correlates with the magnitude of this cellular signaling response.
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