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Anabolic-Catabolic Signaling

Meaning

Anabolic-catabolic signaling describes the continuous, opposing, and tightly regulated communication pathways within all cells that determine whether the body is building up complex molecules or breaking them down for energy. Anabolic signals, such as those from insulin and growth hormone, promote tissue synthesis, while catabolic signals, notably cortisol and glucagon, drive the breakdown of stored resources. The physiological health of the organism depends on a dynamic and context-appropriate balance between these two fundamental metabolic states.