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Amyloid Clearance Pathways

Meaning

Amyloid Clearance Pathways are the specific biological processes and routes utilized by the central nervous system to eliminate or degrade amyloid-beta peptides, which are neurotoxic protein fragments implicated in neurodegenerative conditions. Maintaining robust clearance is critical for preserving neuronal health and cognitive function over the lifespan. Clinical focus is often placed on optimizing these pathways to prevent the accumulation of plaques in the brain parenchyma. Impairment in these systems is a key feature of cognitive decline.