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Amyloid-Beta

Meaning

Amyloid-Beta refers to a short peptide fragment derived from the larger amyloid precursor protein (APP) that exists naturally within the brain. Clinically, it is recognized for its propensity to aggregate into insoluble plaques, a pathological hallmark observed in neurodegenerative conditions. The presence and accumulation of these protein aggregates are central to the structural and functional decline of neural tissue. Understanding its role is critical in the context of hormonal aging, as sex steroids influence its metabolism.