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AMPK Pathway

Meaning

AMPK (Adenosine Monophosphate-activated Protein Kinase) is a cellular energy sensor, a highly conserved serine/threonine protein kinase. It becomes activated when intracellular ATP levels are low, signaling a state of energy depletion and a corresponding increase in the AMP:ATP ratio. This activation initiates cellular processes designed to restore metabolic balance and energy homeostasis.