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Amino Acid Sequencing

Meaning

Amino acid sequencing is the fundamental laboratory technique used to determine the precise linear order of amino acid residues within a peptide or protein molecule. This essential structural information is vital because the sequence dictates the protein’s unique three-dimensional fold, which ultimately governs its specific biological function and clinical activity. Knowledge of the sequence is indispensable for synthesizing therapeutic peptides and understanding the intricate structure-function relationships of hormones in endocrinology.