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Amino Acid Sequence Signaling

Meaning

Amino acid sequence signaling describes the mechanism by which the precise linear order of amino acids within a peptide or protein dictates its biological function and cellular communication role. This specific sequence determines the molecule’s three-dimensional structure, which is essential for its ability to bind to target receptors. Errors or alterations in this sequence can drastically change a peptide’s signaling capability, leading to dysfunction in endocrine pathways. Clinical applications leverage this fundamental principle to design synthetic peptides with predictable and highly specific therapeutic effects.