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Amino Acid Sequence Directives

Meaning

Amino Acid Sequence Directives are the precise, genetically encoded instructions that dictate the linear order in which amino acids must be polymerized to synthesize a specific peptide or protein, such as a circulating hormone or a cellular receptor. This non-negotiable sequence determines the protein’s unique three-dimensional folding pattern, which is the sole determinant of its biological function and signaling efficacy within the complex endocrine network. A deviation in these fundamental directives can result in the creation of a dysfunctional hormone or an impaired signaling molecule, severely impacting homeostatic balance.