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Amino Acid Degradation

Meaning

This metabolic process refers to the breakdown of amino acids, the building blocks of proteins, which occurs when they are present in excess or when the body requires energy from non-carbohydrate sources. The process removes the amino group, typically forming urea for excretion, while the remaining carbon skeletons are converted into intermediates for the citric acid cycle or gluconeogenesis. This pathway is essential for maintaining nitrogen balance and overall energy homeostasis within the human body. Clinically, alterations in this degradation can lead to the accumulation of toxic byproducts, often signaling underlying metabolic disorders.