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Altered Peptide Repertoire

Meaning

This term describes a deviation from the normal spectrum of peptides present in a biological system, which can signify a shift in cellular function or disease state. Peptides are short chains of amino acids that serve as signaling molecules, hormones, or building blocks for larger proteins. In endocrinology, an altered repertoire might involve changes in neuropeptides or hormones derived from pro-hormones, impacting systemic regulation. Such alterations are often observed in the context of immune-endocrine interactions or metabolic dysfunction.