A personalized clinical approach focused on optimizing the body’s allostatic capacity—its ability to maintain stability through physiological change—to better anticipate and respond to stressors. This strategy aims to reduce allostatic load, which is the cumulative wear and tear on the body’s systems due to chronic stress and inefficient adaptation. It represents a proactive, high-level physiological management plan.
Origin
The concept is rooted in the neuroendocrinology of stress, specifically building upon the foundational work of allostasis, which describes the process of achieving stability through physiological change. The term ‘Readiness Strategy’ applies this concept to a preventative and performance-optimizing clinical framework.
Mechanism
The strategy operates by modulating the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system, optimizing the dynamic balance of cortisol, DHEA, and catecholamines. By enhancing hormonal resilience and improving stress recovery, it increases the physiological buffer against environmental and metabolic challenges, thus maintaining homeostasis more effectively.
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