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Allopregnanolone Metabolism

Meaning

The biochemical process of synthesis, transformation, and breakdown of the neurosteroid allopregnanolone within the body. This process is crucial for regulating its concentration, which directly impacts central nervous system function. It involves a series of enzymatic reactions that convert precursor steroids, primarily progesterone, into this potent gamma-aminobutyric acid type A (GABA-A) receptor modulator. Maintaining balance in this metabolic pathway is essential for optimal neurological and hormonal health.