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Allopregnanolone Function

Meaning

Allopregnanolone function refers to the biological actions of this potent neurosteroid, a derivative of progesterone, which acts as a positive allosteric modulator of the GABA-A receptor in the central nervous system. This neuroactive metabolite is crucial for regulating mood, anxiety, sleep, and cognitive processes. Clinically, fluctuations in its concentration are often implicated in conditions like premenstrual dysphoric disorder and postpartum depression, highlighting its role in neurological homeostasis.