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Alcoholic Fatty Liver Disease

Meaning

Alcoholic Fatty Liver Disease (AFLD) represents the earliest and most common stage of liver injury resulting from excessive ethanol consumption, characterized by the pathological accumulation of triglycerides within hepatocyte cytoplasm. This hepatic steatosis signifies a critical disruption in the liver’s lipid metabolism, an organ central to hormonal clearance and metabolic regulation throughout the body. The condition is a direct manifestation of chronic toxic exposure, which profoundly impacts the physiological integrity of the hepatic tissue, a key endocrine target organ. Early intervention is crucial as AFLD can progress to more severe forms of alcoholic liver disease, including steatohepatitis and cirrhosis.