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Alcohol-Induced Hypogonadism

Meaning

Alcohol-Induced Hypogonadism is a clinical condition defined by the impaired function of the gonads, resulting in deficient production of endogenous sex hormones, primarily testosterone and estrogen, directly caused by chronic, excessive alcohol consumption. This syndrome presents clinically with reduced libido, sexual dysfunction, diminished secondary sexual characteristics, and often impacts fertility. Chronic ethanol exposure disrupts the intricate signaling cascade of the hypothalamic-pituitary-gonadal (HPG) axis, leading to central or primary endocrine failure. Accurate diagnosis is essential for effective hormonal health management and patient education on lifestyle modification.