Skip to main content

Akt/PKB Pathway

Meaning

The Akt/PKB Pathway is a crucial intracellular signaling cascade that regulates fundamental cellular processes such as metabolism, proliferation, survival, and growth. This network is a key nexus through which cells respond to external stimuli, including hormonal signals like insulin and various growth factors. Its proper function is essential for maintaining cellular homeostasis across all tissues. Dysregulation of this pathway is frequently implicated in the pathophysiology of metabolic disorders like insulin resistance and the progression of certain malignancies.