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AKR1C1

Meaning

AKR1C1 is the abbreviation for Aldo-Keto Reductase Family 1 Member C1, an enzyme crucial for the metabolism of various steroid hormones and prostaglandins. This protein functions as a reductive catalyst, playing a significant role in determining the active concentration of sex steroids within target tissues. Its activity is particularly relevant in the peripheral metabolism of androgens and progestins.