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AGTR1 Gene

Meaning

The AGTR1 gene provides the blueprint for creating the Angiotensin II Receptor Type 1 protein, which serves as the primary docking site for the powerful hormone Angiotensin II. This receptor is integral to the body’s cardiovascular and renal systems, mediating the critical effects of the Renin-Angiotensin-Aldosterone System (RAAS). The function of this gene is essential for regulating blood pressure, fluid volume, and electrolyte balance throughout the lifespan. Genetic variations in AGTR1 can significantly alter receptor function, impacting an individual’s hormonal homeostasis and disease risk.