Aging Science is the multidisciplinary study of the biological processes that underlie the aging process and age-related decline in function across organisms.
Context
This field examines the molecular, cellular, and systemic changes that occur over a lifespan, including alterations in hormonal regulation, metabolic efficiency, and tissue repair mechanisms.
Significance
Insights from aging science are crucial for developing clinical strategies to promote healthy longevity, manage age-associated diseases, and improve the quality of life by addressing the physiological challenges of growing older.
Mechanism
Key mechanisms studied include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and stem cell exhaustion, all of which impact physiological systems.
Application
Clinical applications involve interventions aimed at mitigating age-related functional decline, optimizing hormonal status, and preventing or treating diseases prevalent in older age, such as cardiovascular disease, neurodegenerative disorders, and metabolic syndrome.
Metric
Aging is monitored through various biomarkers, including telomere length, epigenetic clocks, inflammatory markers (e.g., IL-6, TNF-alpha), and assessments of physiological function and frailty.
Risk
Interventions targeting aging processes without a thorough scientific basis or clinical validation may carry risks of unintended physiological consequences, metabolic disruption, or adverse effects on hormonal balance.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.