Aging Male Health pertains to the physiological and psychological changes experienced by men as they mature, with a specific focus on hormonal shifts, metabolic alterations, and their impact on overall well-being and disease susceptibility.
Context
This field is situated within andrology and endocrinology, addressing the typical decline in testosterone and other hormones, and their systemic effects on body composition, mood, energy levels, and sexual function.
Significance
It is crucial for maintaining a high quality of life, physical vitality, cognitive acuity, and sexual health in aging men, while also mitigating risks for conditions such as osteoporosis, cardiovascular disease, and metabolic syndrome.
Mechanism
The primary mechanism involves the gradual decrease in androgen production, particularly testosterone, alongside shifts in growth hormone, cortisol, and thyroid hormone levels, affecting muscle mass, bone density, fat metabolism, and libido.
Application
Clinical applications include testosterone replacement therapy, management of metabolic health through diet and exercise, and strategies to support cardiovascular and bone health, all tailored to the individual’s physiological profile.
Metric
Monitoring involves serum testosterone levels (total and free), LH, FSH, estradiol, SHBG, PSA, lipid profiles, glucose metabolism markers (HbA1c), and bone density scans.
Risk
Potential risks associated with interventions like testosterone replacement therapy include polycythemia, sleep apnea exacerbation, prostate health concerns, and cardiovascular events if not carefully managed and monitored.
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