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Aggregation Kinetics

Meaning

Aggregation Kinetics describes the scientific rate and manner by which individual molecules, particularly proteins or peptides, associate to form larger, often insoluble, aggregates. In the context of hormonal therapeutics and peptide science, this refers to the critical process where a therapeutic agent loses its active, monomeric structure. Understanding these kinetics is vital for predicting a compound’s stability, efficacy, and shelf life within a pharmaceutical formulation. Clinically, accelerated aggregation can lead to a loss of biological activity and potentially trigger unwanted immunogenic responses in a patient.