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Age Trajectory Shift

Meaning

A clinical objective and measurable change in the rate of biological aging, aiming to slow, halt, or potentially reverse the progressive decline in physiological function typically associated with chronological age. This shift is assessed by analyzing validated biological age markers, such as epigenetic clocks and telomere length, rather than solely relying on birth date. Achieving a positive age trajectory shift signifies an improvement in healthspan, allowing for extended years of vitality and disease resistance. It represents a deviation from the individual’s genetically predicted or historical aging curve toward a more youthful biological state.